PATENTS
An Apparatus And Method For Cerebral Microdialysis To Treat Neurological Disease, Including Alzheimer’s, Parkinson’s Or Multiple Sclerosis
Patent Number: US 2019/0009014 Al
Date Filed: January 10, 2019
Country Filed In: USA
Product Application: SINNAIS Implantable Pump
Description:
An apparatus for performing cerebral microdialysis to treat the neurological disease of a patient's brain includes a catheter for implantation in or near the patient's brain, an implantable pump communicated with the catheter to transport cerebraspinal fluid (CSF) from the patient, which CSF contains diseased cells or biomolecules associated with the neurological disease, and an implantable separation device communicated with the pump wherein the diseased cells or biomolecules are removed, where the separation apparatus includes a dialysis membrane impregnated with an antibody, a reversible electrostatic filter, and/or a magnetic field effect fractionation chamber wherein a magnetically-tagged antibody scavenges and aids in the removal of circulating diseased cells or biomolecules from the CSF.
Field of Use: The SINNAIS Implantable Pump is the culmination of over a decade and a half of research and development for an implantable drug delivery pump incorporating Josh Shachar's biosensor technology to provide a step forward in providing patients with a more effective treatment protocol for pharma-based regimens where current systemic drug delivery is not as effective. The SINNAIS system provides metronomically controlled drug delivery at micro-dose levels with SMART biosensor feedback that provides a physician real-time data on a variety of treatment and patient vital metrics to allow for rapid response and modification of treatment from a remote location.