PATENTS

Automated, Cloud-Based, Point-Of-Care (POC) Pathogen And Antibody Array Detection System And Method
Patent Number: US 11,130,994 B2
Date Filed: September 28, 2021
Country Filed In: USA
Product Application: OPTIKUS Pathogen Detection

Description:

The illustrated embodiments of the invention include an automated method of assaying a viral and antibody analyte in a sample in a portable, handheld microfluidic reader having a SAW detector with a minimal mass sensitivity limitation. The automated method includes the steps of automatically performing the assay with the SAW detector with enhanced sensitivity as in OPTIKUS I, but also includes the steps of automatically disposing a second portion of the sample on a microarray, selectively automatically probing the second portion of the sample for antibodies correspond­ing to the at least one selected virus using the microarray, and automatically reading the microarray using a fluorescent camera to identify antibodies in the second portion of the sample.
Field of Use: OPTIKUS is the second generation of portable handheld pathogen detection technologies created by Josh Shachar and his Engineering Team. The device utilized a whole new method of taking a fluid sample and processing it through all steps of biomarker detection on a single microfluidic disc. Once a sample was injected into a septum reservoir on the disc, the disc was inserted into the OPTIKUS Reader. The microfluidic disc allows for fluid separation, conjugation of magnetic nano-beads to the suspected antigens, conjugation of the nano-bead-antigen particles to corresponding antibodies embedded on a biosensor surface, and then detection to occur via surface acoustic wave generation, all within minutes and with clinically relevant results. The reader was also capable of communicating the data through a secure wireless protocol to cloud storage for immediate dissemination and review by applicable healthcare provides.

News Archive