Carbon Nanotube Biofet With A Local Amplifier In A System Array For Analysis Of Biomarkers And Method Of Analysis Of Same

Carbon Nanotube Biofet With A Local Amplifier In A System Array For Analysis Of Biomarkers And Method Of Analysis Of Same

Patent Number: US 2018/0031521 Al

Date Filed: February 1, 2018

Country Filed In: USA

Product Application: bioFET Biosensor

A bioFET cell for measuring a time-dependent characteristic of an analyte bearing fluid includes a source, a drain, a semiconductive single-wall carbon nanotube network layer extending between the source and drain electrodes and electrically coupled therebetween, a gate insulatively spaced from and disposed of over and extending between the source and drain electrodes, a layer of at least one selected antibody disposed on and linked to the polymer layer to functionalize the semiconductive single-wall carbon nano­tube network layer to a selected target biomarker corre­sponding to the at least one selected antibody so that electron transport into the semiconductive single-wall carbon nano­tube network layer is facilitated, where the source, drain and gate electrodes with the carbon nanotube network layer form a defined channel through which the analyte bearing fluid may flow, and a high impedance source follower amplifier coupled to the source electrode.

Field of Use: The bioFET cell is part of Josh Shachar's exploration into developing next-generation biosensors that are capable of detecting specific biomarkers within a sample at clinically relevant levels in a simple portable point-of-care-device that can provide physicians and health-care workers rapid and affordable pathogen detection without the need for a dedicated lab and specialized technicians and all the associated cost therein.