The Use of Local Amplifiers and Huygens Sensor Array in Measuring Bioelectric Signals and Clinical Applications Thereof

The Use of Local Amplifiers and Huygens Sensor Array in Measuring Bioelectric Signals and Clinical Applications Thereof

Patent Number: PHA3PAU63PCT

Date Filed: May 20, 2022

Country Filed In: USA

Product Application: Huygens™ Catheter

The Huygens™ Catheter is the only tool in existence today that can measure both the DC potential as well as the tissue contact impedance (conductivity) for the same tissue area. This enables us to employ the Maxwell second set of time-varying equations, by substituting the magnetic energy vector (MEV) with the Poynting Energy Vector (P) where we substitute the B terms with the impedance measured value Z. The impedance Z is measured nearly simultaneously with the measurement of the electric potential E of the heart wave using separately sensing electrodes on the Huygens catheter and sensing and signal processing circuitry. Since the E and B fields are in temporal quadrature, their strengths cannot be simultaneously measured, but they can be measured in near simultaneity since the sample rate of the Huygens™ Catheter is of the order of 1 kHz compared to the 1Hz beat rate of the heart and the heart wave. Thus, an approximate value of the Poynting vector, E x B, can be measured at any given time, substituting the measured impedance Z for a computed value for B. This is a derivation that was never described in the literature of the causal relationship between conduction path and fibrillation. The mechanism used to describe fibrillation is associated with the theory defined under the heading “phase singularity” whereby the computer on the back-end of the Huygens™ Catheter performs a phase study separating normal tissue from fibrotic/scar tissue. The disclosed technique using the Huygens™ Catheter with the algorithm provided using Maxwell’s equations distinguishes the invention from the existing art. [

Field of Use: The Huygens™ Catheter represents a major advancement in creating a next-generation endocardial-mapping catheter for the electrophysiology arena. Based on the earlier discoveries made with the MOSFET™ Catheter, the Huygens£ Catheter employs the same basic concept of moving all the bioelectric signal measurement, amplification, filtering and data-processing onto a flexible micro-circuit board at the distal end of the catheter in order to mitigate the noise pollution issues associated with current mapping catheter systems. The Huygens™ Catheter provide a wholly new approach to catheter electrode placement and fidelity that allows for the ability to accurately measure extremely small millivolt signals which helps in increasing signal capture and resolution by 200x. Huygens™ also provides real analog to digital signal conversion at the sensor tip to eliminate signal degradation as information is sent to the external mapping station.